Cytiva (formerly part of GE Healthcare Life Sciences) - Cytiva AxiChrom 300/300 Chromotography Column

• Purification of biopharmaceuticals such as antibodies, vaccines, and recombinant proteins.
• Separation and purification in process development and manufacturing within the biotech industry.
• Use in GMP-compliant environments for critical bioprocessing steps.
• Large-scale chromatographic separations requiring high resolution and reproducibility.

Column Inner Diameter

This specific unit has a 300 mm i.d., which is suitable for pilot to production scale.

Bed Height

This unit is configured for a 300 mm bed height, commonly adjustable for this class of equipment to suit various process needs.

Operating Pressure

Typically designed for low-pressure chromatography applications, suitable for soft media.

Materials of Construction

Wetted parts commonly comply with USP Class VI and 21 CFR part 177, ensuring suitability for pharmaceutical use.

Packing Method

Features automated axial compression packing, ensuring reproducible bed density and performance.

Sanitisation

Designed for effective cleaning and sanitisation, including treatment with 1 M NaOH, crucial for GMP compliance.

• What is axial compression chromatography?

  Axial compression chromatography involves applying pressure to the chromatography bed in the axial direction, which helps to maintain bed stability and improve separation efficiency, especially with soft media.

• Is this column suitable for GMP environments?

• What types of media can be used with this column?

• How does the 'swing-out' tube feature benefit operation?

• Can the bed height be adjusted?

Chromatography columns and accessories hold strong reputations within analytical laboratories for reliability and consistent performance. Buyers typically value used equipment that maintains original specifications and comes with documentation of maintenance history. Industry sentiment favours purchasing from reputable sources where column condition, packing integrity, and compatibility with existing systems are verified. Common strengths include durability of quality columns across multiple applications and cost savings versus new purchases. When buying used, inspecting for damage, confirming proper storage conditions, and verifying suitability for intended analytical methods remain critical considerations for laboratory operations.

General overview for this equipment type