QuattroFlow QF15PTIU Single-use Pump Diaphragm Pump

• Filtration systems, including tangential flow filtration (TFF) and virus filtration.
• Chromatography processes, for precise buffer and product transfer.
• Bioreactor feeding and harvesting in sensitive biopharmaceutical environments.
• Aseptic transfer of media, buffers, and drug products.
• Filling and dispensing operations requiring high accuracy and low shear.

Typical Flow Rate Range

For this class of single-use diaphragm pump, flow rates commonly range from approximately 0.02 to 3.2 litres per minute (LPM).

Pumping Mechanism

Typically employs a quaternary (4-piston) diaphragm positive displacement system, designed for gentle product handling.

Materials of Construction (Wetted Parts)

Commonly constructed from disposable machined polypropylene or similar biopharmaceutical-grade plastics, suitable for single-use applications.

Product Containment

Designed for total product containment, minimising abrasion and particle shedding, which is crucial for product purity.

Control System

Units of this type often feature an integrated controller for automated operation and precise flow control.

Certifications

Typically complies with stringent biopharmaceutical standards such as USP Class VI, 3.1B, and CFR FDA regulations.

Shear Sensitivity

Known for low-shear operation, making it suitable for delicate biological products.

• What are the primary benefits of a single-use diaphragm pump?

  Single-use pumps eliminate the need for cleaning and sterilisation validation between batches, significantly reducing turnaround times and mitigating the risk of cross-contamination. They are ideal for sensitive biopharmaceutical applications.

• How does a quaternary diaphragm pump differ from other pump types?

• Is this pump suitable for viscous fluids?

• What kind of maintenance does a single-use pump require?

• Can this pump be integrated into existing bioprocessing systems?

• What is the typical operating pressure range for this equipment?

Diaphragm pumps are generally valued for their reliability and versatility across laboratory and pharmaceutical applications. Buyers typically prioritise condition of the diaphragm itself, seals and valve integrity when purchasing used units. Industry sentiment favours their gentle handling of sensitive fluids, low maintenance requirements and ability to manage viscous or abrasive media. Common strengths include self-priming capability, compact design and suitability for both suction and discharge applications. Durability remains a key selling point.

General overview for this equipment type