Cytiva (formerly part of GE Healthcare Life Sciences) - Cytiva BPG 100/500 Chromatography Column

• Used in biopharmaceutical manufacturing for protein purification and separation.
• Applied in vaccine production for isolating target molecules from complex mixtures.
• Utilised in research and development for process optimisation and scale-up studies.
• Suitable for the purification of plasma derivatives and other biological products.

Column dimensions

For this model, the '100/500' typically indicates a 100 mm internal diameter and a 500 mm bed height, providing a working volume of approximately 3.9 litres.

Materials of construction

Commonly constructed from biocompatible materials such as borosilicate glass and inert polymers (e.g., PEEK, PTFE) for wetted parts.

Operating pressure

Units of this type typically operate at pressures suitable for medium-pressure chromatography, often up to 5 bar.

Temperature range

Designed for operation within a typical laboratory temperature range, commonly 4°C to 40°C.

Flow rate capability

Capable of accommodating flow rates suitable for process-scale applications, typically ranging from tens to hundreds of ml/min, depending on media and back pressure.

Sanitisation

Units are typically designed for easy sanitisation-in-place (SIP) or cleaning-in-place (CIP) using common cleaning agents.

• What is the typical application for a BPG 100/500 column?

  This column size is typically used for pilot-scale or small-scale production, as well as for process development and optimisation in biopharmaceutical purification.

• What kind of chromatography media can be used with this column?

• Are spare parts readily available for Cytiva BPG columns?

• What maintenance is typically required for a chromatography column?

• Can this column be integrated into an automated chromatography system?

Chromatography columns and accessories hold strong reputations within analytical laboratories for reliability and consistent performance. Buyers typically value used equipment that maintains original specifications and comes with documentation of maintenance history. Industry sentiment favours purchasing from reputable sources where column condition, packing integrity, and compatibility with existing systems are verified. Common strengths include durability of quality columns across multiple applications and cost savings versus new purchases. When buying used, inspecting for damage, confirming proper storage conditions, and verifying suitability for intended analytical methods remain critical considerations for laboratory operations.

General overview for this equipment type